Biorevitalizing mesotherapy with increased regenerative activity.

Jalupro® HMW is designed for intensive skin revitalization and regeneration by delivering nutrients and supporting the cellular metabolism of fibroblasts. It uses non-crosslinked hyaluronic acid with higher molecular weight (HMW – High Molecular Weight) combined with amino acids and vitamins.

Compared to classic meso-cocktails, Jalupro® HMW is aimed at more intensive improvement of skin quality—especially where the skin shows reduced elasticity and resilience.

Mechanism of action

Jalupro® HMW works through synergy of active ingredients:

• higher-molecular-weight hyaluronic acid – supports hydration and biomechanical properties of the intercellular space,
• structural amino acids (e.g., glycine, L-proline, L-leucine, L-lysine) – substrates for collagen and elastin synthesis,
• vitamins and coenzymes – support cellular metabolism and skin repair processes.

The formula optimizes extracellular-matrix (ECM) function and stimulates fibroblasts, supporting improved dermal quality.

Clinical effect

After Jalupro® HMW therapy, the following may be observed:

• improved skin hydration,
• increased elasticity and resilience,
• improved texture and smoothness,
• reduced visibility of fine irregularities,
• natural rejuvenation effect without changing facial features.

The effect is gradual and cumulative, especially with a treatment series.

Clinical indications

Jalupro® HMW may be used in patients:

• with reduced skin elasticity,
• with thin, dehydrated or lax skin,
• with signs of aging and loss of firmness,
• in anti-aging and regenerative therapies,
• when deeper revitalization is needed compared to Jalupro® Classic.

Most common areas:

• face (including areas requiring intensive hydration/regeneration),
• neck,
• decolletage,
• other body areas with reduced skin quality.

Therapy characteristics

• needle mesotherapy procedure,
• minimally invasive,
• no volumizing effect,
• no mechanical implantation,
• minimal or no downtime,
• results build over time with a series.

Jalupro HMW in the context of other therapies (overview)

• Jalupro® Classic – baseline skin biorevitalization,
• Jalupro® HMW – more intensive mesotherapy with higher HA profile,
• SUNEKOS® / SUNEKOS® 1200 / Cell15 – biorevitalization and stimulation with different activity profiles,
• LINERASE – collagen biostimulation as a biological matrix,
• AQUASHINE BR – biorevitalization and tone modulation.

Combination therapies

Jalupro® HMW may be:

• used as a standalone therapy,
• an adjunct to regenerative and technology-based procedures (RF, HIFU, Endolift®),
• part of comprehensive anti-aging and skin-quality protocols.

Treatment selection is individualized after medical consultation.

Medical information

Jalupro® HMW treatment is performed after medical qualification. The goal is to support natural skin regeneration by optimizing fibroblast metabolism and extracellular matrix—not mechanical filling or volume change.

Jalupro® HMW is an intensive biorevitalizing mesotherapy designed to improve skin quality using higher-molecular-weight hyaluronic acid and key amino acids.